Ethyl 3-pyridazinone-6-carboxylate

Ethyl 3-pyridazinone-6-carboxylate - Names and Identifiers

Name	Ethyl 3-pyridazinone-6-carboxylate
Synonyms	ethyl-3-pyridazone-6-carboxylate Ethyl 3-pyridazinone-6-carboxylate Ethyl 6-oxopyridazine-3-carboxylate Ethyl 6-hydroxypyridazine-3-carboxylate 6-OXO-3-PYRIDAZINECARBOXYLIC ACID,ETHYL ESTER 1,6-Dihydro-6-Oxo-3-Pyridazinecarboxylic Acid, Ethyl Ester 1,6-DIHYDRO-6-OXO-3-PYRIDAZINECARBOXYLIC ACID, ETHYL ESTER 3-Pyridazinecarboxylic acid, 1,6-dihydro-6-oxo-, ethyl ester
CAS	63001-31-0

Ethyl 3-pyridazinone-6-carboxylate - Physico-chemical Properties

Molecular Formula	C7H8N2O3
Molar Mass	168.15
Density	1.33
Melting Point	127-128 °C
Appearance	Ash powder
pKa	10.41±0.40(Predicted)
Storage Condition	2-8°C

Ethyl 3-pyridazinone-6-carboxylate - Introduction

Ethyl 3-pyriridazine-6-carboxylate (Ethyl 3-pyriridazine-6-carboxylate) is an organic compound whose chemical structure contains a pyridazine ring and an ethyl formate group.

Nature:
-Appearance: It is usually colorless to slightly yellow crystal or crystalline powder.
-Solubility: It is soluble in many organic solvents, such as alcohols, ethers and aromatic hydrocarbons, slightly soluble in water.
-Melting point: Its melting point is about 110-112°C.
-Chemical reactivity: It is a medium-strength base that can react with acid to form the corresponding salt. In some organic reactions, it can also participate as an intermediate.

Use:
- Ethyl 3-pyriridazine-6-carboxylate is commonly used as an intermediate in organic synthesis. It can be used to synthesize a series of bioactive compounds, such as pesticides, pharmaceuticals and ligands.
-Because of its special properties in catalyst, homogeneous catalysis and metal complex preparation, it is also used in some catalytic reactions.

Preparation Method:
- Ethyl 3-pyriridazine-6-carboxylate can be prepared by reacting pyridazinone with ethyl formate. The reaction is generally carried out at an appropriate temperature and ratio of reactants, with the aid of a suitable reaction solvent.
-After the reaction is over, the target product can be purified and harvested by solvent distillation or extraction.

Safety Information:
-The specific harmfulness of Ethyl 3-pyriridazine-6-carboxylate has not been reported.
-It is a chemical and should be handled in accordance with personal protection requirements to avoid inhalation, contact with skin and eyes.

Last Update：2024-04-09 21:04:16